Abstract: Objective To investigate the anxiety situation of elder second pregnant women during the last pregnancy period and determine related influencing factors. Method sThe pregnant women with advanced second trimester pregnancy who underwent antenatal checkup were selected from the obstetrics outpatient clinics of two hospitals in Karamay. A questionnaire survey containing the self-rating anxiety scale, pregnancy stress scale, and simplified coping style was conducted. Descriptive epidemiological analysis was used to analyze the results, and multiple linear regression model was performed to determine factors influencing anxiety of pregnant women in the late pregnancy. Results A total of 1 025 second pregnant women during the late trimester of pregnancy in Karamay City was investigated. The pregnant women aged from 35 to 46 years, with an average age of （38.21 ± 2.06） years and gestational age of （33.62 ± 2.75） weeks. Of the participants, 561 （54.7%） had the education level at undergraduate or above, and 713 （69.6%） had the per capita monthly household income ranging from 3,000 to 6,999 Yuan. Anxiety symptoms were found in 403 cases, with an incidence of 39.32%. The pregnancy anxiety score was（49.65 ± 6.87）,with a scoring rate of 62.06%.The stress score was （0.98 ± 0.04）, with a scoring rate of 49.00%. The scores of positive and negative coping styles were （26.32 ± 2.62） and （9.65 ± 1.87）, and the scoring rates were 73.11% and 40.21%, respectively. Multiple regression analysis showed that the greater gestational age （b=3.624）, history of cesarean section （b=4.504）, history of adverse pregnancy and childbirth （b=5.631）, pregnancy complications （b=2.985）, fetal gender expectation （b= 3.652）, medication during pregnancy （b=3.805）, higher score of negative coping （b=5.847）, and higher score of pregnancy stress （b=4.514） were risk factors for anxiety in pregnant women in the third trimester（b=-3.658）; while having assigned person to take special care after delivery （b=-3.658） and better sleep quality （b=-3.587） were protective factors for anxiety in the late pregnancy. Conclusion The elder second pregnant women generally have anxiety during the third trimester of pregnancy, lower pregnancy stress level, and higher level of positive coping in Karamay City. There are many factors influencing anxiety in late pregnancy.

Key words: Older age, Second trimester, Second pregnancy, Anxiety, Stress, Influencing factors